CCL19

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/CCL19 latin yazuında])
Навигациягә күчү Эзләүгә күчү
CCL19
Нинди таксонда бар акыллы кеше[d][1]
Кодирующий ген CCL19[d][1]
Молекулярная функция CCR10 chemokine receptor binding[d][2], cytokine activity[d][3], chemokine receptor binding[d][4], CCR7 chemokine receptor binding[d][3], chemokine activity[d][5][6], CCR chemokine receptor binding[d][7], связывание с белками плазмы[d][8], chemokine activity[d][3][9][10] һәм CCR chemokine receptor binding[d][11][10]
Күзәнәк компоненты внеклеточная область[d][3][3][3], внутриклеточный[d][5] һәм внеклеточное пространство[d][3][10]
Биологический процесс release of sequestered calcium ion into cytosol[d][12], positive regulation of receptor-mediated endocytosis[d][3], позитивная регуляция сигналов от протеинкиназы В[d][9][13], positive regulation of cell motility[d][9], positive regulation of dendritic cell dendrite assembly[d][3], activation of JUN kinase activity[d][3], positive regulation of interleukin-12 production[d][3], regulation of cell projection assembly[d][3], monocyte chemotaxis[d][10], positive regulation of T-helper 1 cell differentiation[d][3], chemokine-mediated signaling pathway[d][10], response to nitric oxide[d][14], cellular response to tumor necrosis factor[d][10], T cell costimulation[d][3], response to virus[d][15], cellular calcium ion homeostasis[d][15], cell maturation[d][3], myeloid dendritic cell chemotaxis[d][12], positive regulation of JNK cascade[d][9], dendritic cell chemotaxis[d][9], positive regulation of phosphatidylinositol 3-kinase activity[d][9][13], хемотаксис[d][3], cell communication[d][15], positive regulation of endocytosis[d][3], positive regulation of GTPase activity[d][3][10], response to prostaglandin E[d][12], positive regulation of dendritic cell antigen processing and presentation[d][3], positive regulation of chemotaxis[d][3], cellular response to interleukin-1[d][10], positive regulation of T cell proliferation[d][3], иммунный ответ[d][16][3], positive regulation of ERK1 and ERK2 cascade[d][17][6], establishment of T cell polarity[d][18], positive regulation of glycoprotein biosynthetic process[d][3], cellular response to interferon-gamma[d][10], positive regulation of tumor necrosis factor production[d][3], positive regulation of I-kappaB kinase/NF-kappaB signaling[d][13], lymphocyte chemotaxis[d][10], positive regulation of neutrophil chemotaxis[d][19], воспалительная реакция[d][12][3][10], immunological synapse formation[d][3], mature conventional dendritic cell differentiation[d][3], positive regulation of protein kinase activity[d][12][13], antimicrobial humoral immune response mediated by antimicrobial peptide[d][20], regulation of signaling receptor activity[d][3], G protein-coupled receptor signaling pathway[d][3][10], negative regulation of dendritic cell apoptotic process[d][13], cytokine-mediated signaling pathway[d][3], positive regulation of NIK/NF-kappaB signaling[d][13], neutrophil chemotaxis[d][10] һәм positive regulation of ERK1 and ERK2 cascade[d][21][9][10]
Изображение Gene Atlas

CCL19 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[22][23]

Искәрмәләр[үзгәртү | вики-текстны үзгәртү]

  1. 1,0 1,1 UniProt
  2. J Gosling, Dairaghi D. J., Y Wang et al. Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK // J. Immunol.Baltimore: 2000. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.164.6.2851PMID:10706668
  3. 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 3,10 3,11 3,12 3,13 3,14 3,15 3,16 3,17 3,18 3,19 3,20 3,21 3,22 3,23 3,24 3,25 3,26 3,27 3,28 3,29 UniProt-GOA
  4. Watts A. O., Verkaar F., Miranda M C van der Lee et al. β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2013. — ISSN 0021-9258; 1083-351X; 1067-8816doi:10.1074/JBC.M112.406108PMID:23341447
  5. 5,0 5,1 UniProt-GOA
  6. 6,0 6,1 Corbí A. L., Sánchez-mateos P., Rodríguez-Fernández J. L. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed // J. Immunol.Baltimore: 2005. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.174.7.4070PMID:15778365
  7. Catusse J., Hartmann T. N., Nibbs R. J. et al. CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B // ImmunologyWiley-Blackwell, 2010. — ISSN 0019-2805; 1365-2567doi:10.1111/J.1365-2567.2009.03209.XPMID:20002784
  8. Dyer D. P. The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2016. — ISSN 0021-9258; 1083-351X; 1067-8816doi:10.1074/JBC.M116.720953PMID:27044744
  9. 9,0 9,1 9,2 9,3 9,4 9,5 9,6 Corbí A. L., Sánchez-mateos P., Rodríguez-Fernández J. L. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed // J. Immunol.Baltimore: 2005. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.174.7.4070PMID:15778365
  10. 10,00 10,01 10,02 10,03 10,04 10,05 10,06 10,07 10,08 10,09 10,10 10,11 10,12 10,13 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform.OUP, 2011. — ISSN 1467-5463; 1477-4054doi:10.1093/BIB/BBR042PMID:21873635
  11. Catusse J., Hartmann T. N., Nibbs R. J. et al. CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B // ImmunologyWiley-Blackwell, 2010. — ISSN 0019-2805; 1365-2567doi:10.1111/J.1365-2567.2009.03209.XPMID:20002784
  12. 12,0 12,1 12,2 12,3 12,4 Scandella E., Groettrup M., Ludewig B. CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2 // BloodAmerican Society of Hematology, Elsevier, 2004. — ISSN 0006-4971; 1528-0020doi:10.1182/BLOOD-2003-05-1643PMID:14592837
  13. 13,0 13,1 13,2 13,3 13,4 13,5 Cuadrado A., Cabanas C., Corbí A. L. et al. Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells // BloodAmerican Society of Hematology, Elsevier, 2004. — ISSN 0006-4971; 1528-0020doi:10.1182/BLOOD-2003-11-3943PMID:15059845
  14. Clark E. A. Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19 // BloodAmerican Society of Hematology, Elsevier, 2006. — ISSN 0006-4971; 1528-0020doi:10.1182/BLOOD-2005-07-2901PMID:16249377
  15. 15,0 15,1 15,2 Nomiyama H. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7 // J. Biol. Chem. / L. M. GieraschBaltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1997. — ISSN 0021-9258; 1083-351X; 1067-8816doi:10.1074/JBC.272.21.13803PMID:9153236
  16. F Annunziato, P Romagnani, L Cosmi et al. Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: possible implications for negative selection // J. Immunol.Baltimore: 2000. — ISSN 0022-1767; 1550-6606doi:10.4049/JIMMUNOL.165.1.238PMID:10861057
  17. Hsu Y., Wang M., Ho L. et al. Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus // J Cell Mol Med, or JCMMWiley-Blackwell, Wiley, 2015. — ISSN 1582-1838; 1582-4934; 1453-1321doi:10.1111/JCMM.12500PMID:25754930
  18. Bardi G., Niggli V., Loetscher P. Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes // FEBS LettersElsevier, 2003. — ISSN 0014-5793; 1873-3468doi:10.1016/S0014-5793(03)00351-XPMID:12729902
  19. Jaillon S., Doni A. CCR7 is involved in the migration of neutrophils to lymph nodes // BloodAmerican Society of Hematology, Elsevier, 2011. — ISSN 0006-4971; 1528-0020doi:10.1182/BLOOD-2009-11-254490PMID:21051556
  20. Yang D., Chen Q., Hoover D. M. et al. Many chemokines including CCL20/MIP-3alpha display antimicrobial activity. // J. Leukoc. Biol. / L. MontanerWiley-Blackwell, 2003. — ISSN 0741-5400; 1938-3673doi:10.1189/JLB.0103024PMID:12949249
  21. Hsu Y., Wang M., Ho L. et al. Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus // J Cell Mol Med, or JCMMWiley-Blackwell, Wiley, 2015. — ISSN 1582-1838; 1582-4934; 1453-1321doi:10.1111/JCMM.12500PMID:25754930
  22. HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). 18 сентябрь, 2017 тикшерелде.
  23. UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелде.

Чыганаклар[үзгәртү | вики-текстны үзгәртү]

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)