FOXA2

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/FOXA2 latin yazuında])
FOXA2
Нинди таксонда бар H. sapiens[d][1]
Кодирующий ген FOXA2[d][1]
Молекулярная функция ДНК-связывающий[d][2][3], sequence-specific DNA binding[d][2], protein domain specific binding[d][2], DNA-binding transcription factor activity[d][2][3][4][…], transcription factor binding[d][2], RNA polymerase II cis-regulatory region sequence-specific DNA binding[d][5] һәм DNA-binding transcription factor activity, RNA polymerase II-specific[d][6][6][2][…]
Күзәнәк компоненты Цитоплазма[2], нуклеоплазма[d][2], Межклеточные контакты[d][2], Төш[7][8][9][…] һәм Төш[2][3][10][…]
Биологический процесс dopaminergic neuron differentiation[d][11][2][12], regulation of insulin secretion involved in cellular response to glucose stimulus[d][2], ДНК-зависимая регуляция транскрипции[d][2], positive regulation of gastrulation[d][2], response to interleukin-6[d][13], positive regulation of transcription from RNA polymerase II promoter by glucose[d][2], regulation of transcription by RNA polymerase II[d][14], cell fate specification[d][2], adult locomotory behavior[d][2], negative regulation of DNA-binding transcription factor activity[d][5], транскрипция, ДНК-зависимая[d][7], ДНК-зависимая позитивная регуляция транскрипции[d][2][3], multicellular organism development[d][2], negative regulation of glucokinase activity[d][2], negative regulation of detection of glucose[d][2], regulation of blood coagulation[d][15], positive regulation of embryonic development[d][2], primitive streak formation[d][2], negative regulation of epithelial to mesenchymal transition[d][16], endocrine pancreas development[d][4], положительная регуляция транскрипции РНК полимеразой II промотор[d][11][16][4], positive regulation of cell-cell adhesion mediated by cadherin[d][16], морфогенез анатомической структуры[d][17], chromatin organization[d][2], negative regulation of transcription from RNA polymerase II promoter by glucose[d][2], regulation of transcription by RNA polymerase II[d][15][17] һәм дифференцировка клеток[d][17]

FOXA2 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[18][19]

Искәрмәләр[үзгәртү | вики-текстны үзгәртү]

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 2,21 2,22 2,23 2,24 GOA
  3. ↑ 3,0 3,1 3,2 3,3 Y Cui, Narayanan C. S., J Zhou et al. Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression // Gene — Elsevier BV, 1998. — ISSN 0378-1119; 1879-0038 — doi:10.1016/S0378-1119(98)00512-5 — PMID:9931457
  4. ↑ 4,0 4,1 4,2 Egan J. M. Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors // J. Cell. Physio. — Wiley, 2002. — ISSN 0021-9541; 1097-4652 — doi:10.1002/JCP.10143 — PMID:12124776
  5. ↑ 5,0 5,1 Montesinos M. L., Trembleau A. Joint regulation of the MAP1B promoter by HNF3beta/Foxa2 and Engrailed is the result of a highly conserved mechanism for direct interaction of homeoproteins and Fox transcription factors // Development: the journal of the Society for International Development / J. Briscoe — The Company of Biologists, 2003. — 10 p. — ISSN 0950-1991; 1477-9129; 0212-2448; 1011-6370; 1461-7072 — doi:10.1242/DEV.00414 — PMID:12642491
  6. ↑ 6,0 6,1 Vaquerizas J. M., Teichmann S., Kummerfeld S. K. A census of human transcription factors: function, expression and evolution // Nature reviews. Genetics — UK: NPG, 2009. — ISSN 1471-0056; 1471-0064 — doi:10.1038/NRG2538 — PMID:19274049
  7. ↑ 7,0 7,1 GOA
  8. ↑ Y Cui, Narayanan C. S., J Zhou et al. Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression // Gene — Elsevier BV, 1998. — ISSN 0378-1119; 1879-0038 — doi:10.1016/S0378-1119(98)00512-5 — PMID:9931457
  9. ↑ Taggart M. J. Differentiation of human epidermal neural crest stem cells (hEPI-NCSC) into virtually homogenous populations of dopaminergic neurons // Stem Cell Reviews and Reports / K. Türkşen — Springer Science+Business Media, 2014. — ISSN 1550-8943; 1558-6804; 2629-3269; 2629-3277 — doi:10.1007/S12015-013-9493-9 — PMID:24399192
  10. ↑ Taggart M. J. Differentiation of human epidermal neural crest stem cells (hEPI-NCSC) into virtually homogenous populations of dopaminergic neurons // Stem Cell Reviews and Reports / K. Türkşen — Springer Science+Business Media, 2014. — ISSN 1550-8943; 1558-6804; 2629-3269; 2629-3277 — doi:10.1007/S12015-013-9493-9 — PMID:24399192
  11. ↑ 11,0 11,1 E. Arenas Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease // Journal of molecular cell biology — OUP, 2014. — ISSN 1674-2788; 1759-4685 — doi:10.1093/JMCB/MJU001 — PMID:24431302
  12. ↑ Pruszak J., Isacson O. Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway // Cell Stem Cell — Cell Press, Elsevier BV, 2009. — ISSN 1934-5909; 1875-9777 — doi:10.1016/J.STEM.2009.09.015 — PMID:19951692
  13. ↑ Verschuur M., Jong M. d., Felida L. et al. A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2005. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M501973200 — PMID:15737987
  14. ↑ H Ceelie, C C Spaargaren-Van Riel, Jong M. D. et al. Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer // Journal of Thrombosis and Haemostasis — Wiley-Blackwell, 2003. — ISSN 1538-7933; 1538-7836 — doi:10.1046/J.1538-7836.2003.00393.X — PMID:12911579
  15. ↑ 15,0 15,1 H Ceelie, C C Spaargaren-Van Riel, Jong M. D. et al. Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer // Journal of Thrombosis and Haemostasis — Wiley-Blackwell, 2003. — ISSN 1538-7933; 1538-7836 — doi:10.1046/J.1538-7836.2003.00393.X — PMID:12911579
  16. ↑ 16,0 16,1 16,2 Song Y., Washington M. K., Crawford H. C. Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer // Cancer Res. / G. C. Prendergast — American Association for Cancer Research, 2010. — ISSN 0008-5472; 1538-7445 — doi:10.1158/0008-5472.CAN-09-2979 — PMID:20160041
  17. ↑ 17,0 17,1 17,2 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  18. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  19. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар[үзгәртү | вики-текстны үзгәртү]

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


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