CCL21

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/CCL21 latin yazuında])
CCL21
Нинди таксонда бар H. sapiens[d][1]
Кодирующий ген CCL21[d][1]
Молекулярная функция cytokine activity[d][2], chemokine receptor binding[d][3], CCR7 chemokine receptor binding[d][2][2], chemokine activity[d][4][5][6], CCR chemokine receptor binding[d][7], связывание с белками плазмы[d][8][9] һәм chemokine activity[d][2][2][10][…]
Күзәнәк компоненты внеклеточная область[d][2][2][2] һәм внеклеточное пространство[d][2][7]
Биологический процесс negative regulation of leukocyte tethering or rolling[d][10], release of sequestered calcium ion into cytosol[d][11], positive regulation of receptor-mediated endocytosis[d][2], позитивная регуляция сигналов от протеинкиназы В[d][12][13], positive regulation of cell motility[d][12], positive regulation of actin filament polymerization[d][14], monocyte chemotaxis[d][7], activation of GTPase activity[d][12], ruffle organization[d][15], positive regulation of cell-matrix adhesion[d][10][15], chemokine-mediated signaling pathway[d][7], cellular response to tumor necrosis factor[d][7], передача сигнала между клетками[d][16], T cell costimulation[d][2], cell maturation[d][2], positive regulation of JNK cascade[d][12], dendritic cell chemotaxis[d][12], negative regulation of dendritic cell dendrite assembly[d][2], positive regulation of phosphatidylinositol 3-kinase activity[d][12][13], хемотаксис[d][2], response to prostaglandin E[d][11], positive regulation of dendritic cell antigen processing and presentation[d][2], dendritic cell dendrite assembly[d][2], positive regulation of pseudopodium assembly[d][14], mesangial cell-matrix adhesion[d][15], positive regulation of chemotaxis[d][2], cellular response to interleukin-1[d][7], иммунный ответ[d][17][2], establishment of T cell polarity[d][18], positive regulation of ERK1 and ERK2 cascade[d][19][6], positive regulation of glycoprotein biosynthetic process[d][2], cellular response to interferon-gamma[d][7], positive regulation of I-kappaB kinase/NF-kappaB signaling[d][13], cell chemotaxis[d][2][10], lymphocyte chemotaxis[d][7], positive regulation of neutrophil chemotaxis[d][20], positive regulation of cell adhesion mediated by integrin[d][15], immunological synapse formation[d][2], positive regulation of filopodium assembly[d][15], positive regulation of T cell migration[d][21], positive regulation of myeloid dendritic cell chemotaxis[d][11], positive regulation of protein kinase activity[d][13], воспалительная реакция[d][16][11][2][…], antimicrobial humoral immune response mediated by antimicrobial peptide[d][22], regulation of signaling receptor activity[d][2], G protein-coupled receptor signaling pathway[d][4][5], negative regulation of dendritic cell apoptotic process[d][13], G protein-coupled receptor signaling pathway[d][2][10][7], positive regulation of T cell chemotaxis[d][2], neutrophil chemotaxis[d][7], chemokine (C-C motif) ligand 21 signaling pathway[d][2], positive regulation of GTPase activity[d][7], positive regulation of ERK1 and ERK2 cascade[d][18][12][7] һәм cellular response to chemokine[d][2]
Изображение Gene Atlas

CCL21 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[23][24]

Искәрмәләр[үзгәртү | вики-текстны үзгәртү]

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 2,21 2,22 2,23 2,24 2,25 2,26 GOA
  3. ↑ Watts A. O., Verkaar F., Miranda M C van der Lee et al. β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2013. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M112.406108 — PMID:23341447
  4. ↑ 4,0 4,1 GOA
  5. ↑ 5,0 5,1 Lalor P., Adams D. CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow // American Journal of Physiology: Gastrointestinal and Liver Physiology — American Physiological Society, 2008. — ISSN 0193-1857; 1522-1547 — doi:10.1152/AJPGI.00266.2007 — PMID:18308860
  6. ↑ 6,0 6,1 Corbí A. L., Sánchez-mateos P., Rodríguez-Fernández J. L. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed // J. Immunol. — Baltimore: 2005. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.174.7.4070 — PMID:15778365
  7. ↑ 7,00 7,01 7,02 7,03 7,04 7,05 7,06 7,07 7,08 7,09 7,10 7,11 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  8. ↑ Kerjaschki D., Petrova T. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2004. — ISSN 1046-6673; 1533-3450 — doi:10.1097/01.ASN.0000113316.52371.2E — PMID:14978162
  9. ↑ Hundelshausen P. V., Grommes J., Weber C. et al. Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation // Sci. Transl. Med. — AAAS, 2017. — ISSN 1946-6234; 1946-6242 — doi:10.1126/SCITRANSLMED.AAH6650 — PMID:28381538
  10. ↑ 10,0 10,1 10,2 10,3 10,4 Lalor P., Adams D. CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow // American Journal of Physiology: Gastrointestinal and Liver Physiology — American Physiological Society, 2008. — ISSN 0193-1857; 1522-1547 — doi:10.1152/AJPGI.00266.2007 — PMID:18308860
  11. ↑ 11,0 11,1 11,2 11,3 Scandella E., Groettrup M., Ludewig B. et al. CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2 // Blood — American Society of Hematology, Elsevier BV, 2004. — ISSN 0006-4971; 1528-0020 — doi:10.1182/BLOOD-2003-05-1643 — PMID:14592837
  12. ↑ 12,0 12,1 12,2 12,3 12,4 12,5 12,6 Corbí A. L., Sánchez-mateos P., Rodríguez-Fernández J. L. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed // J. Immunol. — Baltimore: 2005. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.174.7.4070 — PMID:15778365
  13. ↑ 13,0 13,1 13,2 13,3 13,4 Cuadrado A., Cabanas C., Corbí A. L. et al. Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells // Blood — American Society of Hematology, Elsevier BV, 2004. — ISSN 0006-4971; 1528-0020 — doi:10.1182/BLOOD-2003-11-3943 — PMID:15059845
  14. ↑ 14,0 14,1 A Müller, B Homey, H Soto et al. Involvement of chemokine receptors in breast cancer metastasis // Nature / M. Skipper — NPG, Springer Science+Business Media, 2001. — ISSN 1476-4687; 0028-0836 — doi:10.1038/35065016 — PMID:11242036
  15. ↑ 15,0 15,1 15,2 15,3 15,4 Schlöndorff D., Wörnle M., Kretzler M. Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells // Kidney Int. — NPG, Elsevier BV, 2004. — ISSN 0085-2538; 1523-1755 — doi:10.1111/J.1523-1755.2004.66037.X — PMID:15569314
  16. ↑ 16,0 16,1 Nomiyama H. Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1997. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.272.31.19518 — PMID:9235955
  17. ↑ F Annunziato, P Romagnani, L Cosmi et al. Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: possible implications for negative selection // J. Immunol. — Baltimore: 2000. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.165.1.238 — PMID:10861057
  18. ↑ 18,0 18,1 Bardi G. Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes, Rho kinase is required for CCR7‐mediated polarization and chemotaxis of T lymphocytes // FEBS Letters — Elsevier BV, 2003. — ISSN 0014-5793; 1873-3468 — doi:10.1016/S0014-5793(03)00351-X — PMID:12729902
  19. ↑ Bardi G. Rho kinase is required for CCR7-mediated polarization and chemotaxis of T lymphocytes, Rho kinase is required for CCR7‐mediated polarization and chemotaxis of T lymphocytes // FEBS Letters — Elsevier BV, 2003. — ISSN 0014-5793; 1873-3468 — doi:10.1016/S0014-5793(03)00351-X — PMID:12729902
  20. ↑ Jaillon S., Doni A. CCR7 is involved in the migration of neutrophils to lymph nodes // Blood — American Society of Hematology, Elsevier BV, 2011. — ISSN 0006-4971; 1528-0020 — doi:10.1182/BLOOD-2009-11-254490 — PMID:21051556
  21. ↑ Chiang Y., Lee F. S. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration // PLOS ONE / PLOS ONE Editors — PLoS, 2013. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0061761 — PMID:23620790
  22. ↑ Yang D., Chen Q., Hoover D. M. et al. Many chemokines including CCL20/MIP-3alpha display antimicrobial activity. // J. Leukoc. Biol. / L. Montaner — Wiley-Blackwell, 2003. — ISSN 0741-5400; 1938-3673 — doi:10.1189/JLB.0103024 — PMID:12949249
  23. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  24. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар[үзгәртү | вики-текстны үзгәртү]

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Миоглобин молекуласы
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Чыганак — https://tt.wikipedia.org/w/index.php?title=CCL21&oldid=4125871