Эчтәлеккә күчү

CD14

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/CD14 latin yazuında])
CD14
Нинди таксонда бар H. sapiens[d][1]
Кодлаучы ген CD14[d][1]
Молекуляр функция lipopolysaccharide binding[d][2], opsonin receptor activity[d][3], lipoteichoic acid binding[d][4], связывание с белками плазмы[d][5][6][7][…], peptidoglycan immune receptor activity[d][8], lipopeptide binding[d][9] һәм lipopolysaccharide binding[d][4][10]
Күзәнәк компоненты Гольджи аппараты[11][6], мембрана[d][11], күзәнәк мембранасы[d][11][12][11][…], күзәнәк тышындагы өлкә[d][11][11], күзәнәк өслеге[d][13], lipopolysaccharide receptor complex[d][14], anchored component of external side of plasma membrane[d][15], липидный рафт[d][13][13][16], anchored component of membrane[d][11], endosome membrane[d][11], экзосома[d][17][18][19][…], наружная сторона клеточной мембраны[d][13], күзәнәк тышындагы мохит[d][13][20], secretory granule membrane[d][11], күзәнәк тышындагы мохит[d][11][21], наружная сторона клеточной мембраны[d][11][10], күзәнәк өслеге[d][11][10], липидный рафт[d][11][11][6][…], lipopolysaccharide receptor complex[d][22][10] һәм экзосома[d][23][24][25]
Биологик процесс toll-like receptor TLR1:TLR2 signaling pathway[d][11], response to bacterium[d][11], toll-like receptor 4 signaling pathway[d][13][13][13], immune system process[d][11], cellular response to diacyl bacterial lipopeptide[d][6], positive regulation of interferon-gamma production[d][13][13], response to magnesium ion[d][11], response to heat[d][11], response to electrical stimulus[d][11], MyD88-dependent toll-like receptor signaling pathway[d][11], рецепторно-опосредованный эндоцитоз[d][11], cellular response to triacyl bacterial lipopeptide[d][6], TRIF-dependent toll-like receptor signaling pathway[d][11], response to tumor necrosis factor[d][11], positive regulation of endocytosis[d][11], cell surface receptor signaling pathway[d][8], response to lipopolysaccharide[d][11], cellular response to lipoteichoic acid[d][4], Фагоцитоз[12], positive regulation of tumor necrosis factor production[d][26][11][4][…], воспалительная реакция[d][13][13], response to ethanol[d][11], I-kappaB kinase/NF-kappaB signaling[d][11], toll-like receptor TLR6:TLR2 signaling pathway[d][11], cellular response to lipopolysaccharide[d][27][13][2], response to molecule of bacterial origin[d][11], positive regulation of type I interferon production[d][13], lipopolysaccharide-mediated signaling pathway[d][13], MyD88-independent toll-like receptor signaling pathway[d][11], апоптоз[d][12], врождённый иммунитет[d][11], Некроптоз[d][11], negative regulation of MyD88-independent toll-like receptor signaling pathway[d][11], apoptotic signaling pathway[d][11], toll-like receptor signaling pathway[d][11], neutrophil degranulation[d][11], positive regulation of NIK/NF-kappaB signaling[d][28], воспалительная реакция[d][11][11][10], lipopolysaccharide-mediated signaling pathway[d][11][10], positive regulation of interferon-gamma production[d][11][11][10], toll-like receptor 4 signaling pathway[d][11][11][11][…], cellular response to lipopolysaccharide[d][26][11][4][…], positive regulation of NIK/NF-kappaB signaling[d][9][10] һәм positive regulation of type I interferon production[d][11][10]
Изображение Gene Atlas

CD14 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[29][30]

Искәрмәләр

[үзгәртү | вики-текстны үзгәртү]
  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 Nicolas W J Schröder, Morath S., Alexander C. et al. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2003. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M212829200 — PMID:12594207
  3. ↑ Schumann R. R., Leong S. R., Flaggs G. W. et al. Structure and function of lipopolysaccharide binding protein // Science / H. Thorp — Northern America: AAAS, 1990. — ISSN 0036-8075; 1095-9203 — doi:10.1126/SCIENCE.2402637 — PMID:2402637
  4. ↑ 4,0 4,1 4,2 4,3 4,4 Nicolas W J Schröder, Morath S., Alexander C. et al. Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2003. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M212829200 — PMID:12594207
  5. ↑ Silveyra P., E. Scott Halstead, Mccormack F. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation // PLOS ONE / PLOS ONE Editors — PLoS, 2015. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0126576 — PMID:25965346
  6. ↑ 6,0 6,1 6,2 6,3 6,4 Triantafilou M., Frederick G J Gamper, Haston R. M. et al. Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2006. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M602794200 — PMID:16880211
  7. ↑ Tanaka M., Murakami K., Ozaki S. et al. DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins // FEBS J. — Wiley-Blackwell, 2010. — ISSN 1742-464X; 0014-2956; 1742-4658; 1432-1033 — doi:10.1111/J.1742-4658.2010.07816.X — PMID:20860622
  8. ↑ 8,0 8,1 D Gupta, Kirkland T. N., S Viriyakosol et al. CD14 is a cell-activating receptor for bacterial peptidoglycan // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 1996. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.271.38.23310 — PMID:8798531
  9. ↑ 9,0 9,1 Schröder N. W. J., Heine H., Alexander C. et al. Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses // J. Immunol. — Baltimore: 2004. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.173.4.2683 — PMID:15294986
  10. ↑ 10,0 10,1 10,2 10,3 10,4 10,5 10,6 10,7 10,8 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  11. ↑ 11,00 11,01 11,02 11,03 11,04 11,05 11,06 11,07 11,08 11,09 11,10 11,11 11,12 11,13 11,14 11,15 11,16 11,17 11,18 11,19 11,20 11,21 11,22 11,23 11,24 11,25 11,26 11,27 11,28 11,29 11,30 11,31 11,32 11,33 11,34 11,35 11,36 11,37 11,38 11,39 11,40 11,41 11,42 11,43 11,44 11,45 11,46 11,47 GOA
  12. ↑ 12,0 12,1 12,2 Devitt A. Human CD14 mediates recognition and phagocytosis of apoptotic cells // Nature / M. Skipper — NPG, Springer Science+Business Media, 1998. — ISSN 1476-4687; 0028-0836 — doi:10.1038/33169 — PMID:9548256
  13. ↑ 13,00 13,01 13,02 13,03 13,04 13,05 13,06 13,07 13,08 13,09 13,10 13,11 13,12 13,13 13,14 GOA
  14. ↑ Christen U. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2001. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M009164200 — PMID:11274165
  15. ↑ Haziot A, Chen S, Ferrero E et al. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage // J. Immunol. — Baltimore: 1988. — ISSN 0022-1767; 1550-6606 — PMID:3385210
  16. ↑ Triantafilou M., Frederick G J Gamper, Haston R. M. et al. Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2006. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M602794200 — PMID:16880211
  17. ↑ Farina A., Lane L., Lescuyer P. et al. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine // Journal of Proteomics — Elsevier BV, 2013. — ISSN 1874-3919; 0165-022X — doi:10.1016/J.JPROT.2013.01.012 — PMID:23376485
  18. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  19. ↑ Gonzalez-Begne M., Lu B., Han X. et al. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT) // J. Proteome Res. / J. Yates — ACS, 2009. — ISSN 1535-3893; 1535-3907 — doi:10.1021/PR800658C — PMID:19199708
  20. ↑ Palmer D. J., Kelly V. C., Smit A. et al. Human colostrum: identification of minor proteins in the aqueous phase by proteomics // Proteomics / L. Stimson — Wiley, 2006. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200500558 — PMID:16502470
  21. ↑ Palmer D. J., Kelly V. C., Smit A. et al. Human colostrum: identification of minor proteins in the aqueous phase by proteomics // Proteomics / L. Stimson — Wiley, 2006. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.200500558 — PMID:16502470
  22. ↑ Christen U. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2 // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2001. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M009164200 — PMID:11274165
  23. ↑ Gonzalez-Begne M., Lu B., Han X. et al. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT) // J. Proteome Res. / J. Yates — ACS, 2009. — ISSN 1535-3893; 1535-3907 — doi:10.1021/PR800658C — PMID:19199708
  24. ↑ Pisitkun T., Tchapyjnikov D., Knepper M. A. Large-scale proteomics and phosphoproteomics of urinary exosomes // Journal of the American Society of Nephrology / J. Briggs — American Society of Nephrology, 2008. — ISSN 1046-6673; 1533-3450 — doi:10.1681/ASN.2008040406 — PMID:19056867
  25. ↑ Sinha A., Kislinger T. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine // Proteomics / L. Stimson — Wiley, 2013. — ISSN 1615-9853; 1615-9861 — doi:10.1002/PMIC.201200561 — PMID:23533145
  26. ↑ 26,0 26,1 Goyert S. M. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice // Immunity — Cell Press, Elsevier BV, 1996. — ISSN 1074-7613; 1097-4180 — doi:10.1016/S1074-7613(00)80254-X — PMID:8612135
  27. ↑ Goyert S. M. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice // Immunity — Cell Press, Elsevier BV, 1996. — ISSN 1074-7613; 1097-4180 — doi:10.1016/S1074-7613(00)80254-X — PMID:8612135
  28. ↑ Schröder N. W. J., Heine H., Alexander C. et al. Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses // J. Immunol. — Baltimore: 2004. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.173.4.2683 — PMID:15294986
  29. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  30. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар

[үзгәртү | вики-текстны үзгәртү]
  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Миоглобин молекуласы
 Бу — аксым турында мәкалә төпчеге.
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Чыганак — https://tt.wikipedia.org/w/index.php?title=CD14&oldid=4125936