ENPP1

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/ENPP1 latin yazuında])
ENPP1
Нинди таксонда бар H. sapiens[d][1]
Кодирующий ген ENPP1[d][1]
Молекулярная функция nucleoside-triphosphate diphosphatase activity[d][2][3][4][…], calcium ion binding[d][5], nucleotide diphosphatase activity[d][6][6][6][…], гомодимеризация белка[d][7][3], insulin receptor binding[d][3], zinc ion binding[d][5], polysaccharide binding[d][5], 3'-phosphoadenosine 5'-phosphosulfate binding[d][3], связывание с ионом металла[d][5][5], scavenger receptor activity[d][5], NADH pyrophosphatase activity[d][5], связывание с белками плазмы[d][8][8], активность катализатора[d][5], nucleic acid binding[d][5], гидролазная активность[d][5][5], АТФ-связанные[d][3], phosphodiesterase I activity[d][6][6][6][…], exonuclease activity[d][9], phosphodiesterase I activity[d][5][5][10][…], nucleotide diphosphatase activity[d][6][6][11][…], nucleotide diphosphatase activity[d][5][12][13] һәм cyclic-GMP-AMP hydrolase activity[d][2]
Күзәнәк компоненты часть мембраны[d][14][5][5], мембрана[d][5], күзәнәк мембраны[d][5][5][10][…], часть клеточной мембраны[d][5], внеклеточная область[d][5], поверхность клетки[d][15], lysosomal membrane[d][16], basolateral plasma membrane[d][17][5], внеклеточное пространство[d][18], lysosomal membrane[d][19] һәм поверхность клетки[d][4][13]
Биологический процесс negative regulation of fat cell differentiation[d][20], negative regulation of protein autophosphorylation[d][8], regulation of bone mineralization[d][15], riboflavin metabolic process[d][5], biomineral tissue development[d][5], nucleoside triphosphate catabolic process[d][15], cellular phosphate ion homeostasis[d][18], negative regulation of glycogen biosynthetic process[d][8], Рецепторно-опосредованный эндоцитоз[d][5], generation of precursor metabolites and energy[d][12], 3'-phosphoadenosine 5'-phosphosulfate metabolic process[d][3], negative regulation of glucose import[d][21], negative regulation of insulin receptor signaling pathway[d][3][21], negative regulation of cell growth[d][21], иммунный ответ[d][5], cellular response to insulin stimulus[d][3][21], phosphate-containing compound metabolic process[d][4][18], Метаболизм[6], inorganic diphosphate transport[d][15], sequestering of triglyceride[d][21], ATP metabolic process[d][6], nucleic acid phosphodiester bond hydrolysis[d][9], nucleoside triphosphate catabolic process[d][4][13], regulation of bone mineralization[d][4][13], inorganic diphosphate transport[d][4][13], negative regulation of fat cell differentiation[d][21][13], ATP metabolic process[d][5][13], vesicle-mediated transport[d][5], melanocyte differentiation[d][7], negative regulation of bone mineralization[d][5], negative regulation of hh target transcription factor activity[d][5] һәм Эндоцитоз[d][5]

ENPP1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[22][23]

Искәрмәләр[үзгәртү | вики-текстны үзгәртү]

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,0 2,1 Yin Q. Hydrolysis of 2'3'-cGAMP by ENPP1 and design of nonhydrolyzable analogs // Nature Chemical Biology — NPG, 2014. — ISSN 1552-4450; 1552-4469 — doi:10.1038/NCHEMBIO.1661 — PMID:25344812
  3. ↑ 3,0 3,1 3,2 3,3 3,4 3,5 3,6 3,7 Maddux B. A., P Sbraccia, S Kumakura et al. Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus // Nature / M. Skipper — NPG, Springer Science+Business Media, 1995. — ISSN 1476-4687; 0028-0836 — doi:10.1038/373448A0 — PMID:7830796
  4. ↑ 4,0 4,1 4,2 4,3 4,4 4,5 K Johnson, S Vaingankar, Y Chen et al. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes // Arthritis Rheumatol — Wiley, Wiley-Blackwell, 1999. — ISSN 2326-5191; 2326-5205 — <1986::AID-ANR26>3.0.CO;2-O doi:10.1002/1529-0131(199909)42:9<1986::AID-ANR26>3.0.CO;2-O — PMID:10513816
  5. ↑ 5,00 5,01 5,02 5,03 5,04 5,05 5,06 5,07 5,08 5,09 5,10 5,11 5,12 5,13 5,14 5,15 5,16 5,17 5,18 5,19 5,20 5,21 5,22 5,23 5,24 5,25 5,26 5,27 5,28 5,29 5,30 GOA
  6. ↑ 6,00 6,01 6,02 6,03 6,04 6,05 6,06 6,07 6,08 6,09 GOA
  7. ↑ 7,0 7,1 Boussofara L., Wong P., Foo J. N. et al. ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis // J. Invest. Dermatol. / M. C. Udey — NPG, Elsevier BV, 2017. — ISSN 0022-202X; 1523-1747 — doi:10.1016/J.JID.2017.08.045 — PMID:28964717
  8. ↑ 8,0 8,1 8,2 8,3 L Frittitta The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121) // Diabetes — American Diabetes Association, 2001. — ISSN 0012-1797; 1939-327X — doi:10.2337/DIABETES.50.4.831 — PMID:11289049
  9. ↑ 9,0 9,1 Martensen P. M., Vestergaard A. L., Andersen K. R. Characterization of human phosphodiesterase 12 and identification of a novel 2'-5' oligoadenylate nuclease - The ectonucleotide pyrophosphatase/phosphodiesterase 1. // Biochimie / R. Buckingham — Elsevier BV, 2012. — ISSN 0300-9084; 1638-6183 — doi:10.1016/J.BIOCHI.2012.01.012 — PMID:22285541
  10. ↑ 10,0 10,1 Rutsch F. Effects of Different Variants in the ENPP1 Gene on the Functional Properties of Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1 // Hum. Mutat. — Wiley, 2016. — ISSN 1059-7794; 1098-1004 — doi:10.1002/HUMU.23057 — PMID:27467858
  11. ↑ Johnson K. One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist, One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist // Arthritis Rheumatol — Wiley, Wiley-Blackwell, 2003. — ISSN 2326-5191; 2326-5205 — doi:10.1002/ART.10927 — PMID:12746903
  12. ↑ 12,0 12,1 Johnson K. One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist, One of two chondrocyte‐expressed isoforms of cartilage intermediate‐layer protein functions as an insulin‐like growth factor 1 antagonist // Arthritis Rheumatol — Wiley, Wiley-Blackwell, 2003. — ISSN 2326-5191; 2326-5205 — doi:10.1002/ART.10927 — PMID:12746903
  13. ↑ 13,0 13,1 13,2 13,3 13,4 13,5 13,6 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  14. ↑ I. Funakoshi, H. Kato, K. Horie et al. Molecular cloning of cDNAs for human fibroblast nucleotide pyrophosphatase // Arch. Biochem. Biophys. — Academic Press, Elsevier BV, 1992. — ISSN 0003-9861; 1096-0384 — doi:10.1016/0003-9861(92)90504-P — PMID:1315502
  15. ↑ 15,0 15,1 15,2 15,3 K Johnson, S Vaingankar, Y Chen et al. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes // Arthritis Rheumatol — Wiley, Wiley-Blackwell, 1999. — ISSN 2326-5191; 2326-5205 — <1986::AID-ANR26>3.0.CO;2-O doi:10.1002/1529-0131(199909)42:9<1986::AID-ANR26>3.0.CO;2-O — PMID:10513816
  16. ↑ Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // Traffic — Wiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854 — doi:10.1111/J.1600-0854.2007.00643.X — PMID:17897319
  17. ↑ Goding J. W., R Terkeltaub, M Maurice et al. Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family // Immunological Reviews — Blackwell Publishing, 1998. — ISSN 0105-2896; 1600-065X — doi:10.1111/J.1600-065X.1998.TB01568.X — PMID:9553761
  18. ↑ 18,0 18,1 18,2 K Johnson, P Schauerte, Kalhoff H. PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification // Am. J. Pathol. — Elsevier BV, 2001. — ISSN 0002-9440; 1525-2191; 0097-3599 — doi:10.1016/S0002-9440(10)63996-X — PMID:11159191
  19. ↑ Schröder B., Wrocklage C., Pan C. et al. Integral and associated lysosomal membrane proteins // Traffic — Wiley-Blackwell, 2007. — ISSN 1398-9219; 1600-0854 — doi:10.1111/J.1600-0854.2007.00643.X — PMID:17897319
  20. ↑ Liang J., Fu M., Ciociola E. et al. Role of ENPP1 on adipocyte maturation // PLOS ONE / PLOS ONE Editors — PLoS, 2007. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0000882 — PMID:17849011
  21. ↑ 21,0 21,1 21,2 21,3 21,4 21,5 Liang J., Fu M., Ciociola E. et al. Role of ENPP1 on adipocyte maturation // PLOS ONE / PLOS ONE Editors — PLoS, 2007. — ISSN 1932-6203 — doi:10.1371/JOURNAL.PONE.0000882 — PMID:17849011
  22. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  23. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар[үзгәртү | вики-текстны үзгәртү]

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Миоглобин молекуласы
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