NODAL

Wikipedia — ирекле энциклопедия проектыннан ([http://tt.wikipedia.org.ttcysuttlart1999.aylandirow.tmf.org.ru/wiki/NODAL latin yazuında])
NODAL
Нинди таксонда бар H. sapiens[d][1]
Кодирующий ген NODAL[d][1]
Молекулярная функция receptor ligand activity[d][2], cytokine activity[d][2][3], type I activin receptor binding[d][4], morphogen activity[d][5], transforming growth factor beta receptor binding[d][3], growth factor activity[d][2][2] һәм type I activin receptor binding[d][6][3]
Күзәнәк компоненты внеклеточная область[d][2][2], внеклеточное пространство[d][7][8] һәм внеклеточное пространство[d][2][9][3]
Биологический процесс trophectodermal cellular morphogenesis[d][2], left lung morphogenesis[d][2], nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry[d][2], neural fold formation[d][2], maternal process involved in parturition[d][2], cell fate commitment[d][2], endoderm development[d][2], transforming growth factor beta receptor signaling pathway involved in primitive streak formation[d][2], floor plate morphogenesis[d][2], endodermal cell differentiation[d][10], epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification[d][2], SMAD protein signal transduction[d][2][3], embryonic pattern specification[d][2], polarity specification of proximal/distal axis[d][2], positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry[d][2], digestive system development[d][2], positive regulation of cell-cell adhesion[d][11], развитие лёгких[d][2], positive regulation of epithelial cell proliferation[d][9], Плацентация[d][6], negative regulation of cell differentiation[d][2], positive regulation of pathway-restricted SMAD protein phosphorylation[d][12], mesoderm formation[d][2], negative regulation of androgen receptor signaling pathway[d][9], gastrulation with mouth forming second[d][2], anatomical structure formation involved in morphogenesis[d][2], positive regulation of DNA-binding transcription factor activity[d][11], regulation of stem cell population maintenance[d][13], formation of anatomical boundary[d][2], embryonic placenta development[d][2], in utero embryonic development[d][2], negative regulation of transcription by RNA polymerase II[d][2], negative regulation of trophoblast cell migration[d][6], tissue morphogenesis[d][2], BMP signaling pathway[d][3], нерв системасы үсеше[d][2], positive regulation of angiogenesis[d][11][2], embryonic heart tube development[d][2], nodal signaling pathway[d][2], stem cell population maintenance[d][2], multicellular organism development[d][2], heart looping[d][2], embryonic process involved in female pregnancy[d][2], развитие сердца[d][2], positive regulation of cysteine-type endopeptidase activity involved in apoptotic process[d][14], развитие мозга[d][2], axial mesodermal cell fate specification[d][2], vasculature development[d][2], positive regulation of activin receptor signaling pathway[d][14], determination of left/right symmetry[d][2], maternal placenta development[d][2], regulation of signal transduction[d][2], Гаструляция[d][2], trophectodermal cell differentiation[d][2], mesendoderm development[d][10][2], позитивная регуляция пролиферации клеток[d][2], positive regulation of ERK1 and ERK2 cascade[d][11], embryonic cranial skeleton morphogenesis[d][2], развитие печени[d][2], positive regulation of vascular endothelial growth factor production[d][11], cell migration involved in gastrulation[d][2], negative regulation of chorionic trophoblast cell proliferation[d][14], anterior/posterior axis specification[d][2], миграция клеток[d][2], regulation of gastrulation[d][2], primitive streak formation[d][2], negative regulation of cell development[d][2], положительная регуляция транскрипции РНК полимеразой II промотор[d][2], морфогенез пищеварительного тракта[d][2], positive regulation of SMAD protein signal transduction[d][10], anterior/posterior pattern specification[d][2], inhibition of neuroepithelial cell differentiation[d][2], развитие клеток[d][3], regulation of signaling receptor activity[d][2], positive regulation of pathway-restricted SMAD protein phosphorylation[d][10][3], regulation of apoptotic process[d][3] һәм regulation of MAPK cascade[d][3]

NODAL (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.[15][16]

Искәрмәләр[үзгәртү | вики-текстны үзгәртү]

  1. ↑ 1,0 1,1 UniProt
  2. ↑ 2,00 2,01 2,02 2,03 2,04 2,05 2,06 2,07 2,08 2,09 2,10 2,11 2,12 2,13 2,14 2,15 2,16 2,17 2,18 2,19 2,20 2,21 2,22 2,23 2,24 2,25 2,26 2,27 2,28 2,29 2,30 2,31 2,32 2,33 2,34 2,35 2,36 2,37 2,38 2,39 2,40 2,41 2,42 2,43 2,44 2,45 2,46 2,47 2,48 2,49 2,50 2,51 2,52 2,53 2,54 2,55 2,56 2,57 2,58 2,59 2,60 2,61 2,62 2,63 GOA
  3. ↑ 3,00 3,01 3,02 3,03 3,04 3,05 3,06 3,07 3,08 3,09 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
  4. ↑ Dunk C., Caniggia I., Lye S. Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia // Am. J. Pathol. — Elsevier BV, 2011. — ISSN 0002-9440; 1525-2191; 0097-3599 — doi:10.1016/J.AJPATH.2010.11.066 — PMID:21356369
  5. ↑ Postovit L. Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype // Cancer Res. / G. C. Prendergast — American Association for Cancer Research, 2010. — 11 p. — ISSN 0008-5472; 1538-7445 — doi:10.1158/0008-5472.CAN-10-0705 — PMID:21159651
  6. ↑ 6,0 6,1 6,2 Dunk C., Caniggia I., Lye S. Nodal signals through activin receptor-like kinase 7 to inhibit trophoblast migration and invasion: implication in the pathogenesis of preeclampsia // Am. J. Pathol. — Elsevier BV, 2011. — ISSN 0002-9440; 1525-2191; 0097-3599 — doi:10.1016/J.AJPATH.2010.11.066 — PMID:21356369
  7. ↑ GOA
  8. ↑ Lawrence M. G., Loessner D., Postovit L. et al. Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells // Prostate — Wiley, 2011. — ISSN 0270-4137; 1097-0045 — doi:10.1002/PROS.21335 — PMID:21656830
  9. ↑ 9,0 9,1 9,2 Lawrence M. G., Loessner D., Postovit L. et al. Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells // Prostate — Wiley, 2011. — ISSN 0270-4137; 1097-0045 — doi:10.1002/PROS.21335 — PMID:21656830
  10. ↑ 10,0 10,1 10,2 10,3 Kim S. W., Yoon S., Chuong E. et al. Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs // Dev. Biol. — Elsevier BV, 2011. — ISSN 0012-1606; 1095-564X — doi:10.1016/J.YDBIO.2011.06.009 — PMID:21741376
  11. ↑ 11,0 11,1 11,2 11,3 11,4 Lin G. Inhibition of Nodal suppresses angiogenesis and growth of human gliomas // Journal of Neuro-Oncology — Springer Science+Business Media, 2010. — ISSN 0167-594X; 1573-7373 — doi:10.1007/S11060-010-0467-3 — PMID:21116837
  12. ↑ Kim S. W., Yoon S., Chuong E. et al. Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCs // Dev. Biol. — Elsevier BV, 2011. — ISSN 0012-1606; 1095-564X — doi:10.1016/J.YDBIO.2011.06.009 — PMID:21741376
  13. ↑ Adrian Kee Keong Teo, Hannan N., Vardy L. et al. Activin/Nodal signaling controls divergent transcriptional networks in human embryonic stem cells and in endoderm progenitors // Stem Cells — Wiley, AlphaMed Press, 2011. — ISSN 1066-5099; 1549-4918 — doi:10.1002/STEM.666 — PMID:21630377
  14. ↑ 14,0 14,1 14,2 Munir S., Xu G., Wu Y. et al. Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells // J. Biol. Chem. / L. M. Gierasch — Baltimore [etc.]: American Society for Biochemistry and Molecular Biology, 2004. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M400641200 — PMID:15150278
  15. ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
  16. ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.

Чыганаклар[үзгәртү | вики-текстны үзгәртү]

  • Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
  • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)


Миоглобин молекуласы
 Бу — аксым турында мәкалә төпчеге.
Сез мәкаләне үзгәртеп һәм мәгълүмат өстәп, Википедия проектына ярдәм итә аласыз.
Чыганак — https://tt.wikipedia.org/w/index.php?title=NODAL&oldid=4132113